Article
Relating the outcome of HCV infection and different host SNP polymorphisms in a Majorcan population coinfected with HCV-HIV and treated with pegIFN-RBV.
International microbiology : the official journal of the Spanish Society for Microbiology - 1 Mar 2014
Matas Marina, Picornell Antònia, Cifuentes Carmen, Payeras Antoni, Homar Francesc, González-Candelas Fernando, López-Labrador F Xavier, Moya Andrés, Ramon Cori, Castro José A
Abstract excerpt
Hepatitis C virus (HCV) is one of the major causes of chronic hepatitis, cirrhosis, and hepatocellular carcinoma, and the development of HCV-related disease is accelerated in individuals coinfected with human immunodeficiency-1 virus (HIV). In the present study, we correlated different host single-nucleotide polymorphisms (SNPs) in the IL28B, CTLA4, LDLr, and HFE genes and mitochondrial DNA (mtDNA) haplogroups...
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