Article
Refined analysis of genetic variability parameters in hepatitis C virus and the ability to predict antiviral treatment response.
Journal of viral hepatitis - 1 Aug 2008
Cuevas J M, Torres-Puente M, Jiménez-Hernández N, Bracho M A, García-Robles I, Carnicer F, Olmo J D, Ortega E, Moya A, González-Candelas F
Abstract excerpt
Hepatitis C virus (HCV) infects approximately 3% of the world population. The chronicity of hepatitis C seems to depend on the level of genetic variability. We have recently (Torres-Puente et al., J Viral Hepat, 2008; 15: 188) reported genetic variability estimates from a large-scale sequence analysis of 67 patients infected with HCV subtypes 1a (23 patients) and 1b (44 patients) and related them to response, or...
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