Article
Maternally inherited susceptibility to cancer.
Biochimica et biophysica acta - 1 Jun 2011
Bayona-Bafaluy María Pilar, López-Gallardo Ester, Montoya Julio, Ruiz-Pesini Eduardo
Abstract excerpt
Tumor microenvironment promotes mtDNA mutations. A number of these mutations will affect cell metabolism and increase cell survival. These mutations are positively selected and contribute to other tumor features, such as extracellular matrix remodeling and angiogenic processes, thus favoring meta...
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