Article
Phenotyping breast cancer cell lines EM-G3, HCC1937, MCF7 and MDA-MB-231 using 2-D electrophoresis and affinity chromatography for glutathione-binding proteins.
BMC cancer - 23 Aug 2010
Mladkova Jana, Sanda Miloslav, Matouskova Eva, Selicharova Irena
Abstract excerpt
BACKGROUND: Transformed phenotypes are common to cell lines derived from various cancers. Proteome profiling is a valuable tool that may reveal uncharacteristic cell phenotypes in transformed cells. Changes in expression of glutathione S-transferases (GSTs) and other proteins interacting with glutathione (GSH) in model cell lines could be of particular interest. METHODS: We compared the phenotypes of breast cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
