Article
Identification of tumor-associated protein variants during rat hepatocarcinogenesis. Aldose reductase.
The Journal of biological chemistry - 20 May 1994
Zeindl-Eberhart E, Jungblut P R, Otto A, Rabes H M
Abstract excerpt
Tumor-associated protein variants were detected by two-dimensional gel electrophoresis (2-DE) in soluble proteins from chemically induced rat hepatomas and transformed rat liver cell lines. Among them, a series of 8 protein variants was found localized at similar sites in 2-DE gels (33-35 kDa, with different pI values). We characterized four of them. In situ peptide mapping with limited proteolysis disclosed a...
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