Article
Specific-locus experiments show that female mice exposed near the time of birth to low-LET ionizing radiation exhibit both a low mutational response and a dose-rate effect.
Mutation research - 1 Aug 1991
Selby P B, Lee S S, Kelly E M, Bangham J W, Raymer G D, Hunsicker P R
Abstract excerpt
Female mice were exposed to 300 R of 73-93 R/min X-radiation either as fetuses at 18.5 d post conception (p.c.) or within 9 h after birth. Combining the similar results from these two groups yielded a specific-locus mutation frequency of 9.4 X 10(-8) mutation/locus/R, which is statistically signi...
Topics
- Alleles
- Animals
- Animals, Newborn
- Cell Survival
- Dose-Response Relationship, Radiation
- Energy Transfer
- Female
- Fertility
- Fetus
- Litter Size
- Mice
- Mutation
- Oocytes
- Radiation, Ionizing
- Risk Factors
- Selection, Genetic
- Sex Factors
