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Article

Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: a genetic association study and meta-analysis.

Journal of human genetics - 1 Nov 2010

Zintzaras Elias, Grammatikou Maria, Kitsios Georgios D, Doxani Chrysa, Zdoukopoulos Nikos, Papandreou Christos, Patrikidou Anna

Abstract excerpt

The endothelial nitric oxide synthase gene (NOS3) has been proposed as a candidate gene for breast cancer (BC), however, the specific role of variants and haplotypes has not been clarified. We examined the association of two polymorphisms (4b/a and G894T) and their haplotypes in a case-control sample of 306 patients with BC and in 131 healthy females. In addition, a meta-analysis of studies investigating...

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Source

Identifiers

PMID: 20720556
DOI: 10.1038/jhg.2010.100

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: a genetic association study and meta-analysis.PMID 20720556Read ↗

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