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Article

Intron 4 VNTR (4a/b) polymorphism of the endothelial nitric oxide synthase gene is associated with breast cancer in Mexican women.

Journal of Korean medical science - 1 Nov 2013

Ramírez-Patiño Ramiro, Figuera Luis Eduardo, Puebla-Pérez Ana María, Delgado-Saucedo Jorge Iván, Legazpí-Macias María Magdalena, Mariaud-Schmidt Rocio Patricia, Ramos-Silva Adriana, Gutiérrez-Hurtado Itzae Adonai, Gómez Flores-Ramos Liliana, Zúñiga-González Guillermo Moisés, Gallegos-Arreola Martha Patricia

Abstract excerpt

The endothelial nitric oxide synthase (eNOS) gene plays an important role in several biological functions. Polymorphisms of the eNOS gene have been associated with cancer. It has been suggested that the VNTR 4 a/b polymorphism may affect the expression of eNOS and contributes to tumor promotion in the mammary gland. We examined the role of the eNOS4 a/b polymorphism by comparing the genotypes of 281 healthy...

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Identifiers

PMID: 24265520
DOI: 10.3346/jkms.2013.28.11.1587
PMCID: PMC3835499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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