Article
Cone degeneration following rod ablation in a reversible model of retinal degeneration.
Investigative ophthalmology & visual science - 1 Jan 2011
Choi Rene Y, Engbretson Gustav A, Solessio Eduardo C, Jones Georgette A, Coughlin Adam, Aleksic Ilija, Zuber Michael E
Abstract excerpt
PURPOSE: Amphibian retinas regenerate after injury, making them ideal for studying the mechanisms of retinal regeneration, but this leaves their value as models of retinal degeneration in question. The authors asked whether the initial cellular changes after rod loss in the regenerative model Xenopus laevis mimic those observed in nonregenerative models. They also asked whether rod loss was reversible. METHODS:...
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