Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Murine cytomegalovirus perturbs endosomal trafficking of major histocompatibility complex class I molecules in the early phase of infection.

Journal of virology - 1 Nov 2010

Tomas Maja Ilić, Kucić Natalia, Mahmutefendić Hana, Blagojević Gordana, Lucin Pero

Abstract excerpt

Murine cytomegalovirus (MCMV) functions interfere with protein trafficking in the secretory pathway. In this report we used Δm138-MCMV, a recombinant virus with a deleted viral Fc receptor, to demonstrate that MCMV also perturbs endosomal trafficking in the early phase of infection. This perturbation had a striking impact on cell surface-resident major histocompatibility complex class I (MHC-I) molecules due to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endosomes
Share to Herpesviridae Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Muromegalovirus

Share to Protein Transport

Share to Receptors, Chemokine

Share to Time Factors

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 20719942
DOI: 10.1128/JVI.00988-10
PMCID: PMC2953186

Genes

EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Murine cytomegalovirus perturbs endosomal trafficking of major histocompatibility complex class I molecules in the early phase of infection.PMID 20719942Read ↗

Viral Interference with B7-1 Costimulation: A New Role for Murine Cytomegalovirus Fc Receptor-1Semantic proximity Read ↗

Infection-Induced Changes Within the Endocytic Recycling Compartment Suggest a Roadmap of Human Cytomegalovirus EgressSemantic proximity Read ↗

Cytomegaloviral control of MHC class I function in the mouse.Semantic proximity Read ↗

The luminal part of the murine cytomegalovirus glycoprotein gp40 catalyzes the retention of MHC class I molecules.Semantic proximity Read ↗

Murine cytomegalovirus degrades MHC class II to colonize the salivary glandsSemantic proximity Read ↗

The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responsesSemantic proximity Read ↗

The Multiple Immune-Evasion Genes of Murine Cytomegalovirus Are Not RedundantSemantic proximity Read ↗

Murine Cytomegalovirus Protein pM49 Interacts with pM95 and Is Critical for Viral Late Gene Expression.Semantic proximity Read ↗

A Targeted Spatial-Temporal Proteomics Approach Implicates Multiple Cellular Trafficking Pathways in Human Cytomegalovirus Virion MaturationSemantic proximity Read ↗

Sorting signals in the measles virus wild-type glycoproteins differently influence virus spread in polarized epithelia and lymphocytes.Semantic proximity Read ↗

Spatial Relationships between Markers for Secretory and Endosomal Machinery in Human Cytomegalovirus-Infected Cells versus Those in Uninfected CellsSemantic proximity Read ↗

Cytomegalovirus immune evasion sets the functional avidity threshold for protection by CD8 T cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.