Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients

Abstract excerpt

BACKGROUND: Molecular chaperones have been shown to be important in the growth of the malaria parasite Plasmodium falciparum and inhibition of chaperone function by pharmacological agents has been shown to abrogate parasite growth. A recent study has demonstrated that clinical isolates of the parasite have distinct physiological states, one of which resembles environmental stress response showing up-regulation of...

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