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Article

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

5 Jan 2010

Abstract excerpt

BACKGROUND: In October 2009 it was reported that 68 of 101 patients with chronic fatigue syndrome (CFS) in the US were infected with a novel gamma retrovirus, xenotropic murine leukaemia virus-related virus (XMRV), a virus previously linked to prostate cancer. This finding, if confirmed, would have a profound effect on the understanding and treatment of an incapacitating disease affecting millions worldwide. We...

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Identifiers

PMID: 20066031
DOI: 10.1371/journal.pone.0008519

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue SyndromePMID 20066031Read ↗

No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue SyndromeSemantic proximity Read ↗

No Evidence of Murine-Like Gammaretroviruses in CFS Patients Previously Identified as XMRV-InfectedSemantic proximity Read ↗

Failure to detect Xenotropic murine leukaemia virus-related virus in Chinese patients with chronic fatigue syndromeSemantic proximity Read ↗

Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndromeSemantic proximity Read ↗

Biology and pathophysiology of the new human retrovirus XMRV and its association with human disease.Semantic proximity Read ↗

Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequencesSemantic proximity Read ↗

Multiple sources of contamination in samples from patients reported to have XMRV infection.Semantic proximity Read ↗

Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohortSemantic proximity Read ↗

PCR Master Mixes Harbour Murine DNA Sequences. Caveat Emptor!Semantic proximity Read ↗

No Evidence of XMRV or Related Retroviruses in a London HIV-1-Positive Patient CohortSemantic proximity Read ↗

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer.Semantic proximity Read ↗

Disease-associated XMRV sequences are consistent with laboratory contaminationSemantic proximity Read ↗

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