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Article

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology.

Brain : a journal of neurology - 1 Jul 2009

Simunovic Filip, Yi Ming, Wang Yulei, Macey Laurel, Brown Lauren T, Krichevsky Anna M, Andersen Susan L, Stephens Robert M, Benes Francine M, Sonntag Kai C

Abstract excerpt

Parkinson's disease is caused by a progressive loss of the midbrain dopamine (DA) neurons in the substantia nigra pars compacta. Although the main cause of Parkinson's disease remains unknown, there is increasing evidence that it is a complex disorder caused by a combination of genetic and environmental factors, which affect key signalling pathways in substantia nigra DA neurons. Insights into pathogenesis of...

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Identifiers

PMID: 19052140
DOI: 10.1093/brain/awn323
PMCID: PMC2724914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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