Article
Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism.
Neurobiology of disease - 1 Feb 2005
Greene James G, Dingledine Raymond, Greenamyre J Timothy
Abstract excerpt
To elucidate factors related to selective dopamine neuron degeneration in Parkinson's disease (PD), we have defined gene expression profiles of discrete dopamine neuron subpopulations in the rat using immunofluorescent laser capture microscopy and microarray analysis. Although profiles were remarkably similar, there are concerted categorical differences in gene expression between dopamine neurons that might...
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