Article
Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.
The Journal of experimental medicine - 30 Aug 2010
Fafi-Kremer Samira, Fofana Isabel, Soulier Eric, Carolla Patric, Meuleman Philip, Leroux-Roels Geert, Patel Arvind H, Cosset François-Loïc, Pessaux Patrick, Doffoël Michel, Wolf Philippe, Stoll-Keller Françoise, Baumert Thomas F
Abstract excerpt
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is universal. The mechanisms by which the vir...
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