Article
Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis.
Genes & development - 15 Aug 2010
Govin Jérôme, Dorsey Jean, Gaucher Jonathan, Rousseaux Sophie, Khochbin Saadi, Berger Shelley L
Abstract excerpt
Profound epigenetic differences exist between genomes derived from male and female gametes; however, the nature of these changes remains largely unknown. We undertook a systematic investigation of chromatin reorganization during gametogenesis, using the model eukaryote Saccharomyces cerevisiae to examine sporulation, which has strong similarities with higher eukaryotic spermatogenesis. We established a mutational...
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