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Article

Immunoassay for human serum hemojuvelin.

Haematologica - 1 Dec 2010

Brasse-Lagnel Carole, Poli Maura, Lesueur Céline, Grandchamp Bernard, Lavoinne Alain, Beaumont Carole, Bekri Soumeya

Abstract excerpt

BACKGROUND: Hemojuvelin, a critical regulator of iron homeostasis, is involved in the regulation of hepcidin expression and iron homeostasis. It is expressed both as a membrane-bound form and as a soluble one. Serum hemojuvelin can be produced by secretion following furin cleavage or by proteolytic cleavage of the membrane-bound form by matriptase 2 (TMPRSS6). These forms contribute to down-regulation of hepcidin...

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Source

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Identifiers

PMID: 20713458
DOI: 10.3324/haematol.2010.022129
PMCID: PMC2995560

Genes

TMPRSS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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