Article
Family relationship of female breeders reduce the systematic inter-individual variation in the gut microbiota of inbred laboratory mice.
Laboratory animals - 1 Oct 2010
Hufeldt M R, Nielsen D S, Vogensen F K, Midtvedt T, Hansen A K
Abstract excerpt
The gut microbiota (GM) may influence disease expression in several animal models for inflammatory diseases. It may therefore seem reasonable to pursue reduction in the number of animals used for individual studies by reducing the variation in the GM. Previous studies have shown that the composition of the GM is related to genetics to a certain extent. We hypothesized that the GM similarity in a group of mice...
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