Article
Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice.
Genome biology - 24 Jan 2013
Hildebrand Falk, Nguyen Thi Loan Anh, Brinkman Brigitta, Yunta Roberto Garcia, Cauwe Benedicte, Vandenabeele Peter, Liston Adrian, Raes Jeroen
Abstract excerpt
BACKGROUND: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global understanding of the mouse microbiota landscape. Here, we investigate the variability of the healthy mouse microbiota of five common lab mouse strains using 16S rDNA...
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