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Article

ICAM-1 mediates surface contact between neutrophils and keratocytes following corneal epithelial abrasion in the mouse.

Experimental eye research - 1 Nov 2010

Gagen Debjani, Laubinger Sara, Li Zhijie, Petrescu Matei S, Brown Evelyn S, Smith C Wayne, Burns Alan R

Abstract excerpt

Corneal epithelial abrasion elicits an inflammatory response involving neutrophil (PMN) recruitment from the limbal vessels into the corneal stroma. These migrating PMNs make surface contact with collagen and stromal keratocytes. Using mice deficient in PMN integrin CD18, we previously showed that PMN contact with stromal keratocytes is CD18-dependent, while contact with collagen is CD18-independent. In the...

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Share to Cell Adhesion Molecules
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epithelium, Corneal

Share to Fluorescent Antibody Technique, Indirect

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Source

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Identifiers

PMID: 20713042
DOI: 10.1016/j.exer.2010.08.007
PMCID: PMC2962773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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