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Article

Antigen-presenting cells are stratified within normal human corneas and are rapidly mobilized during ex vivo viral infection.

Investigative ophthalmology & visual science - 24 Feb 2014

Knickelbein Jared E, Buela Kristine-Ann, Hendricks Robert L

Abstract excerpt

PURPOSE: To define the phenotype and location of antigen-presenting cells (APCs) in normal donor human corneas, and to assess the response of APC to herpes simplex virus type 1 (HSV-1) infection. METHODS: Donor human corneal tissue was analyzed by fluorescence confocal microscopy and flow cytometry to determine the phenotype and location of tissue-resident APCs. Confocal fluorescence microscopy was also utilized...

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Identifiers

PMID: 24508792
DOI: 10.1167/iovs.13-13523
PMCID: PMC3934539

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APC

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