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Article

The effects of replacing Sst2 with the heterologous RGS4 on polarization and mating in yeast.

Biophysical journal - 9 Aug 2010

Tanaka Hiromasa, Yi Tau-Mu

Abstract excerpt

RGS proteins stimulate the deactivation of heterotrimeric G-proteins. The yeast RGS protein Sst2 is regulated at both the transcriptional and posttranscriptional levels. We replaced the SST2 gene with the distantly related human RGS4 gene, which consists of the catalytic domain and an N-terminal membrane attachment peptide, and replaced the native promoter (P(SST2)) with the heterologous tetracycline-repressible...

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Source

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Identifiers

PMID: 20712983
DOI: 10.1016/j.bpj.2010.04.078
PMCID: PMC2920719

Genes

RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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