Article
Norovirus recombinants: recurrent in the field, recalcitrant in the lab - a scoping review of recombination and recombinant types of noroviruses.
The Journal of general virology - 1 Aug 2018
Ludwig-Begall Louisa F, Mauroy Axel, Thiry Etienne
Abstract excerpt
Noroviruses are recognized as the major global cause of sporadic and epidemic non-bacterial gastroenteritis in humans. Molecular mechanisms driving norovirus evolution are the accumulation of point mutations and recombination. Intragenotypic recombination has long been postulated to be a driving force of GII.4 noroviruses, the predominant genotype circulating in humans for over two decades. Increasingly,...
Topics
- Animals
- Caliciviridae Infections
- Gene Expression Regulation, Viral
- Genotype
- Humans
- Norovirus
- Reassortant Viruses
