Article
Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.
Journal of virology - 1 Oct 2007
Thackray Larissa B, Wobus Christiane E, Chachu Karen A, Liu Bo, Alegre Eric R, Henderson Kenneth S, Kelley Scott T, Virgin Herbert W
Abstract excerpt
Viruses within the genus Norovirus of the family Caliciviridae are the major cause of acute, nonbacterial gastroenteritis worldwide. Human noroviruses are genetically diverse, with up to 57% divergence in capsid protein sequences, and comprise three genogroups. The significance of such genetic diversity is not yet understood. The discovery of murine norovirus (MNV) and its ability to productively infect cultured...
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