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Recombination in Enteroviruses, a Multi-Step Modular Evolutionary Process

14 Sept 2019

Abstract excerpt

RNA recombination is a major driving force in the evolution and genetic architecture shaping of enteroviruses. In particular, intertypic recombination is implicated in the emergence of most pathogenic circulating vaccine-derived polioviruses, which have caused numerous outbreaks of paralytic poliomyelitis worldwide. Recent experimental studies that relied on recombination cellular systems mimicking natural...

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PMID: 31540135
DOI: 10.3390/v11090859

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