Article
Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.
Diabetologia - 1 Dec 2016
Williams Georgina M, Long Anna E, Wilson Isabel V, Aitken Rachel J, Wyatt Rebecca C, McDonald Timothy J, Wong F Susan, Hattersley Andrew T, Williams Alistair J K, Bingley Polly J, Gillespie Kathleen M
Abstract excerpt
AIMS/HYPOTHESIS: This study aimed to determine the frequency of residual beta cell function in individuals with long-standing type 1 diabetes who were recruited at diagnosis, and relate this to baseline and current islet autoantibody profile. METHODS: Two hour post-meal urine C-peptide:creatinine ratio (UCPCR) and islet autoantibodies were measured in samples collected from 144 participants (median age at...
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