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Article

Baseline β-Cell Secretory Reserve and Its Association with Glycaemic Control and Long-Term Outcomes Across Diabetes Phenotypes.

International journal of molecular sciences - 21 Feb 2026

Maciulewski Rafał, Buczyńska-Backiel Angelika, Zielińska-Maciulewska Anna, Siewko Katarzyna, Krętowski Adam, Szelachowska Małgorzata

Abstract excerpt

Residual β-cell secretory function plays a central role in diabetes pathophysiology; however, long-term comparative data describing β-cell trajectories from diagnosis across diabetes phenotypes remain limited. In this prospective observational study, 393 adults with newly diagnosed diabetes underwent assessment of fasting and glucagon-stimulated C-peptide at diagnosis. The cohort included individuals with type 1...

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Blood Glucose
C-Peptide
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Fasting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin-Secreting Cells

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Identifiers

PMID: 41752170
DOI: 10.3390/ijms27042035
PMCID: PMC12940418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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