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Article

Estrogen receptor alpha gene polymorphisms and first-ever intracerebral hemorrhage.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2007

Strand Magnus, Söderström Ingegerd, Wiklund Per-Gunnar, Hallmans Göran, Weinehall Lars, Söderberg Stefan, Olsson Tommy

Abstract excerpt

BACKGROUND: Signaling through estrogen receptor alpha (ER alpha) regulates vasodilatation and atherogenesis. Since hypertension and atherosclerosis are major mechanisms in stroke development, we hypothesized that genetic variants of the ER alpha gene (ESR1) are determinants of future ischemic stroke or intracerebral hemorrhage (ICH). METHODS: In a population-based prospective nested case-control study, the...

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Source

Identifiers

PMID: 17971628
DOI: 10.1159/000110419

Genes

DBP
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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