Article
[Genetic variations affect drug safety and efficacy].
Nederlands tijdschrift voor geneeskunde - 1 Jan 2010
Harmsze Ankie M, Deneer Vera H, Maitland-van der Zee Anke Hilse, de Boer Anthonius, Klungel Olaf H
Abstract excerpt
Pharmacogenetics is a field that deals with the relationship between genetic variations and the effects and side-effects of drugs. Genetic variations in drug-metabolizing enzymes, transporters, receptors, and other drug targets have been linked to interindividual differences in the efficacy and safety of many drugs. Genotyping is performed increasingly in primary and secondary health care in patients with...
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