Article
[Pharmacogenomics. What is relevant for the internal medicine specialist?].
Der Internist - 1 Dec 2003
Krüth P, Wehling M
Abstract excerpt
Epidemiological observational studies have shown existing interindividual and interethnical differences in drug metabolism. This results in a great variety of effects and side effects of drugs. One reason for these variabilities are genetic polymorphisms which occur on the basis of single-nucleotide exchanges or insertional and deletional mutations. Such mutations may involve transport proteins or metabolizing...
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