Article
[Drug therapy and pharmacogenomics--hopes and facts].
Wiener medizinische Wochenschrift (1946) - 1 Feb 2005
Müller-Zellenberg Ulrike, Müller Markus
Abstract excerpt
Recent achievements in molecular genetics, in particular the characterization of a large number of non-synonymous single-nucleotide polymorphisms (ns-SNPs) have led to a substantial accumulation of knowledge about the mechanisms of interindividual variability in drug response. The concept of elucidating drug reactions by genetic analysis is termed "pharmacogenomics". Pharmacogenomics is set to provide a relevant...
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