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Impact of Pharmacogenomics in Clinical Practice

13 Nov 2023

Abstract excerpt

Polymorphisms of genes encoding drug metabolizing enzymes and transporters can significantly modify pharmacokinetics, and this can be associated with significant differences in drug efficacy, safety, and tolerability. Moreover, genetic variants of some components of the immune system can explain clinically relevant drug-related adverse events. However, the implementation of drug dose individualization based on...

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PMID: 38004461
DOI: 10.3390/ph16111596

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