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Article

T-cell receptor complex is essential for Fas signal transduction.

Proceedings of the National Academy of Sciences of the United States of America - 24 Aug 2010

Akimzhanov Askar M, Wang Xinmin, Sun Jiaren, Boehning Darren

Abstract excerpt

The Fas receptor (also known as CD95 and APO-1) is a member of the tumor necrosis factor alpha-family of death receptors that mediate T-cell responses. Here, we show that Fas receptor signaling requires a functional T-cell receptor (TCR) complex. Fas receptor directly binds to and activates TCR c...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20696918
DOI: 10.1073/pnas.1005419107
PMCID: PMC2930531

Genes

ZAP70

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20696918-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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