Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparison of the usefulness of nuclear beta-catenin in the diagnosis of desmoid-type fibromatosis among commonly used anti-beta-catenin antibodies.

Pathology international - 1 Jun 2021

Yamada Yosuke, Hirata Masahiro, Sakamoto Akio, Noguchi Takashi, Ito Kan, Nishida Yoshihiro, Matsuda Shuichi, Haga Hironori

Abstract excerpt

Desmoid-type fibromatosis (DF) is a locally aggressive but non-metastatic (myo)fibroblastic neoplasm. A hallmark of the tumor is nuclear positivity for beta-catenin in immunohistochemistry due mostly to CTNNB1 mutations. However, a recent study has reported that even beta-catenin 'nuclear-negative' DFs can harbor CTNNB1 mutations and that the positive ratio of nuclear beta-catenin in DF is different among...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neoplasm
Share to beta Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Desmoid Tumors

Share to Diagnosis, Differential

Share to Immunohistochemistry

Share to Infant

Share to Soft Tissue Neoplasms

Source

Identifiers

PMID: 33788979
DOI: 10.1111/pin.13096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparison of the usefulness of nuclear beta-catenin in the diagnosis of desmoid-type fibromatosis among commonly used anti-beta-catenin antibodies.PMID 33788979Read ↗

Clinicopathological features of 70 desmoid-type fibromatoses confirmed by β-catenin immunohistochemical staining and CTNNB1 mutation analysis.Semantic proximity Read ↗

Immunohistochemical staining with non-phospho β-catenin as a diagnostic and prognostic tool of COX-2 inhibitor therapy for patients with extra-peritoneal desmoid-type fibromatosis.Semantic proximity Read ↗

Diagnostic utility of LEF1 and β-catenin in WNT pathway tumors with CTNNB1 mutationSemantic proximity Read ↗

Desmoid fibromatosis: is the current picture changing?Semantic proximity Read ↗

Desmoplastic fibroma of bone: an immunohistochemical study including beta-catenin expression and mutational analysis for beta-catenin.Semantic proximity Read ↗

CTNNB1 Mutational analysis enhances diagnostic precision in β-catenin-negative desmoid fibromatosis: a clinicopathological and molecular study.Semantic proximity Read ↗

Desmoid-Type Fibromatosis: Who, When, and How to Treat.Semantic proximity Read ↗

Biology and Treatment of Aggressive Fibromatosis or Desmoid Tumor.Semantic proximity Read ↗

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature ReviewSemantic proximity Read ↗

Differential diagnosis and mutation stratification of desmoid-type fibromatosis on MRI using radiomics.Semantic proximity Read ↗

Trends in diagnostic and therapeutic strategies for extra-abdominal desmoid-type fibromatosis: Japanese musculoskeletal oncology group questionnaire survey.Semantic proximity Read ↗

Resection of a desmoid-type fibromatosis with a CTNNB1 p.S45P mutation using a cervico-thoracic approach: A case report and literature review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.