Robust estimation and testing of haplotype effects in case-control studies.

Abstract excerpt

Haplotype-based analyses are thought to play a major role in the study of common complex diseases. This has led to the development of a variety of statistical methods for detecting disease-haplotype associations from case-control study data. However, haplotype phase is often uncertain when only genotype data is available. Methods that account for haplotype ambiguity by modeling the distribution of haplotypes can,...

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