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Article

Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia.

Neurobiology of aging - 1 Apr 2012

Proitsi Petroula, Lupton Michelle K, Reeves Suzanne J, Hamilton Gillian, Archer Nicola, Martin Belinda M, Iyegbe Conrad, Hollingworth Paul, Lawlor Brian, Gill Michael, Brayne Carol, Rubinsztein David C, Owen Michael J, Williams Julie, Lovestone Simon, Powell John F

Abstract excerpt

Genetic association studies investigating the association between genes of serotonergic and dopaminergic systems and behavioral and psychological symptoms in dementia (BPSD) are contradictory. We have utilized 1008 probable Alzheimer's disease (AD) patients from the UK and used the 12-item Neuropsychiatric Inventory. We applied a multiple indicators-multiple causes (MIMIC) approach to investigate the effect of 11...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20685009
DOI: 10.1016/j.neurobiolaging.2010.06.011

Genes

DRD4
DRD1
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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