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Article

Differentiation of induced pluripotent stem cells to thymic epithelial cells by phenotype.

Immunology and cell biology - 1 Feb 2011

Inami Yuta, Yoshikai Tohru, Ito Sachiko, Nishio Naomi, Suzuki Haruhiko, Sakurai Hidetoshi, Isobe Ken-Ichi

Abstract excerpt

Thymic epithelial cells (TECs) are present in both cortical and medullary thymic areas, and have crucial roles in functional T-cell development. In this study, we studied the differentiation of induced pluripotent stem cells (iPSCs) to TEC. When iPSC were cultured for 4 days in collagen IV-coated dishes in the presence of both activin A and lithium chloride (LiCl), the cells differentiated to definitive endoderm...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20680027
DOI: 10.1038/icb.2010.96

Genes

BMP4
TEC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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