Article
Identification and characterization of thymic epithelial progenitor cells.
Immunity - 1 Jun 2002
Bennett Andrea R, Farley Alison, Blair Natalie F, Gordon Julie, Sharp Linda, Blackburn C Clare
Abstract excerpt
T cell differentiation and repertoire selection depend critically on several distinct thymic epithelial cell types, whose lineage relationships are unclear. We have investigated these relationships via functional analysis of the epithelial populations within the thymic primordium. Here, we show that mAbs MTS20 and MTS24 identify a population of cells that, when purified and grafted ectopically, can differentiate...
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