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Article

Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis.

Genes & development - 1 Aug 2010

Klusmann Jan-Henning, Godinho Frank J, Heitmann Kirsten, Maroz Aliaksandra, Koch Mia Lee, Reinhardt Dirk, Orkin Stuart H, Li Zhe

Abstract excerpt

Oncogene-mediated transformation of hematopoietic cells has been studied extensively, but little is known about the molecular basis for restriction of oncogenes to certain target cells and differential cellular context-specific requirements for oncogenic transformation between infant and adult leukemias. Understanding cell type-specific interplay of signaling pathways and oncogenes is essential for developing...

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Identifiers

PMID: 20679399
DOI: 10.1101/gad.1903410
PMCID: PMC2912563

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GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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