Article
Consistency of predictive signature genes and classifiers generated using different microarray platforms.
The pharmacogenomics journal - 1 Aug 2010
Fan X, Lobenhofer E K, Chen M, Shi W, Huang J, Luo J, Zhang J, Walker S J, Chu T-M, Li L, Wolfinger R, Bao W, Paules R S, Bushel P R, Li J, Shi T, Nikolskaya T, Nikolsky Y, Hong H, Deng Y, Cheng Y, Fang H, Shi L, Tong W
Abstract excerpt
Microarray-based classifiers and associated signature genes generated from various platforms are abundantly reported in the literature; however, the utility of the classifiers and signature genes in cross-platform prediction applications remains largely uncertain. As part of the MicroArray Quality Control Phase II (MAQC-II) project, we show in this study 80-90% cross-platform prediction consistency using a large...
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