Article
A paradigm for class prediction using gene expression profiles.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2002
Radmacher Michael D, McShane Lisa M, Simon Richard
Abstract excerpt
We propose a general framework for prediction of predefined tumor classes using gene expression profiles from microarray experiments. The framework consists of 1) evaluating the appropriateness of class prediction for the given data set, 2) selecting the prediction method, 3) performing cross-validated class prediction, and 4) assessing the significance of prediction results by permutation testing. We describe an...
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