Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myocilin and optineurin coding variants in Hispanics of Mexican descent with POAG.

Journal of human genetics - 1 Oct 2010

McDonald Kristin K, Abramson Karen, Beltran Marco A, Ramirez Maria G, Alvarez Miguel, Ventura Alice, Santiago-Turla Cecilia, Schmidt Silke, Hauser Michael A, Allingham R Rand

Abstract excerpt

Coding variants in both myocilin (MYOC) and optineurin (OPTN) are reported risk factors for primary open-angle glaucoma (POAG) in many populations. This study investigated the contribution of MYOC and OPTN coding variants in Hispanics of Mexican descent with and without POAG. We conducted a case-control study of unrelated POAG cases and nonglaucomatous controls in a population of Hispanics of Mexican descent....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glaucoma, Open-Angle

Share to Glycoproteins

Share to Hispanic or Latino

Share to Mexican Americans

Share to Mexico

Share to Transcription Factor TFIIIA

Source

Open in PubMed Open full text

Identifiers

PMID: 20668460
DOI: 10.1038/jhg.2010.91
PMCID: PMC2967733

Genes

MYOC
OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myocilin and optineurin coding variants in Hispanics of Mexican descent with POAG.PMID 20668460Read ↗

Identification of a novel MYOC variant in a Hispanic family with early-onset primary open-angle glaucoma with elevated intraocular pressure.Semantic proximity Read ↗

Role of MYOC and OPTN sequence variations in Spanish patients with primary open-angle glaucoma.Semantic proximity Read ↗

SNPs and interaction analyses of myocilin, optineurin, and apolipoprotein E in primary open angle glaucoma patients.Semantic proximity Read ↗

Myocilin variants in Indian patients with open-angle glaucoma.Semantic proximity Read ↗

Comprehensive analysis of myocilin variants in east Indian POAG patients.Semantic proximity Read ↗

Novel and known MYOC exon 3 mutations in an admixed Peruvian primary open-angle glaucoma population.Semantic proximity Read ↗

Identification of a novel MYOC mutation in a Chinese family with primary open-angle glaucoma.Semantic proximity Read ↗

Myocilin gene mutations: A cause of juvenile open-angle glaucoma in north IndiaSemantic proximity Read ↗

Absence of myocilin and optineurin mutations in a large Philippine family with juvenile onset primary open angle glaucoma.Semantic proximity Read ↗

Presence of myocilin sequence variants in Japanese patients with open-angle glaucoma.Semantic proximity Read ↗

Genetic dissection of myocilin glaucoma.Semantic proximity Read ↗

Low prevalence of myocilin mutations in an African American population with primary open-angle glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.