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Article

Absence of myocilin and optineurin mutations in a large Philippine family with juvenile onset primary open angle glaucoma.

Molecular vision - 9 Nov 2004

Wang Dan Yi, Fan Bao Jian, Canlas Oscar, Tam Pancy O S, Ritch Robert, Lam Dennis S C, Fan Dorothy S P, Pang Chi Pui

Abstract excerpt

PURPOSE: To analyze the role of the two primary open angle glaucoma (POAG) genes, myocilin (MYOC) and optineurin (OPTN), in a large Philippine family segregating autosomal dominant juvenile onset open angle glaucoma (JOAG). METHODS: The coding sequences of the MYOC and OPTN genes were screened in 27 family members by polymerase chain reaction and direct sequencing. The specific MYOC promoter polymorphism...

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Source

Identifiers

PMID: 15547491

Genes

MYOC
OPTN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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