Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of MYOC and OPTN sequence variations in Spanish patients with primary open-angle glaucoma.

Molecular vision - 14 Jun 2007

Lopez-Martinez Francisco, Lopez-Garrido Maria-Pilar, Sanchez-Sanchez Francisco, Campos-Mollo Ezequiel, Coca-Prados Miguel, Escribano Julio

Abstract excerpt

PURPOSE: To retrospectively investigate the contribution of myocilin (MYOC) and optineurin (OPTN) sequence variations to adult-onset ocular hypertension (OHT) and primary open-angle glaucoma (POAG) in Spanish patients. METHODS: The promoter region and the three exons of MYOC were analyzed by direct PCR DNA sequencing in 40 OHT and 110 POAG unrelated patients. We used 98 subjects in whom OHT or glaucoma had been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glaucoma, Open-Angle

Share to Glycoproteins

Share to Open Reading Frames

Share to Polymorphism, Single-Stranded Conformational

Share to Transcription Factor TFIIIA

Source

Open in PubMed Open full text

Identifiers

PMID: 17615537
PMCID: PMC2770203

Genes

MYOC
OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of MYOC and OPTN sequence variations in Spanish patients with primary open-angle glaucoma.PMID 17615537Read ↗

Mutations in the third exon of the MYOC gene in spanish patients with primary open angle glaucoma.Semantic proximity Read ↗

Absence of myocilin and optineurin mutations in a large Philippine family with juvenile onset primary open angle glaucoma.Semantic proximity Read ↗

Mutations in MYOC gene of Indian primary open angle glaucoma patients.Semantic proximity Read ↗

MYOC gene mutations in Spanish patients with autosomal dominant primary open-angle glaucoma: a founder effect in southeast Spain.Semantic proximity Read ↗

Myocilin and optineurin coding variants in Hispanics of Mexican descent with POAG.Semantic proximity Read ↗

SNPs and interaction analyses of myocilin, optineurin, and apolipoprotein E in primary open angle glaucoma patients.Semantic proximity Read ↗

MYOC mutation frequency in primary open-angle glaucoma patients from Western Switzerland.Semantic proximity Read ↗

[Single nucleotide polymorphisms of the myocilin gene in primary open-angle glaucoma patients].Semantic proximity Read ↗

Variations in the myocilin gene in patients with open-angle glaucoma.Semantic proximity Read ↗

Polymorphisms in the myocilin promoter unrelated to the risk and severity of primary open-angle glaucoma.Semantic proximity Read ↗

Mutations in the myocilin gene in families with primary open-angle glaucoma and juvenile open-angle glaucoma.Semantic proximity Read ↗

[Polymorphisms of myocilin and optineurin in primary open angle glaucoma patients].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.