Article
Low prevalence of myocilin mutations in an African American population with primary open-angle glaucoma.
Molecular vision - 1 Jan 2012
Liu Wenjing, Liu Yutao, Challa Pratap, Herndon Leon W, Wiggs Janey L, Girkin Christopher A, Allingham R Rand, Hauser Michael A
Abstract excerpt
PURPOSE: Mutations in the myocilin gene (MYOC) are associated with primary open-angle glaucoma (POAG) in many different populations. This study represents the first large survey of MYOC mutations in an African American population. METHODS: We recruited 529 African American subjects with POAG and 270 African American control subjects in this study. A complete eye examination and blood collection was performed in...
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