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Article

HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Sept 2010

von Wyl Viktor, Ehteshami Maryam, Demeter Lisa M, Bürgisser Philippe, Nijhuis Monique, Symons Jori, Yerly Sabine, Böni Jürg, Klimkait Thomas, Schuurman Rob, Ledergerber Bruno, Götte Matthias, Günthard Huldrych F

Abstract excerpt

BACKGROUND: Factors promoting the emergence of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) connection domain mutations and their effect on antiretroviral therapy (ART) are still largely undetermined. We investigated this matter by analyzing genotypic resistance tests co...

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Identifiers

PMID: 20666602
DOI: 10.1086/655764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20666602-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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