Article
Lithium induces mortality in medulloblastoma cell lines.
International journal of oncology - 1 Sept 2010
Ronchi Alice, Salaroli Roberta, Rivetti Stefano, Della Bella Elena, Di Tomaso Tiziano, Voltattorni Manuela, Cammelli Silvia, Ceccarelli Claudio, Giangaspero Felice, Barbieri Enza, Cenacchi Giovanna
Abstract excerpt
Lithium is the main therapeutic agent for the treatment of bipolar disorders but nerve cells are not the sole target of this drug. Indeed, lithium has been reported to target numerous cell types and to affect cell proliferation, differentiation and death. Lithium targets a variety of enzymes amon...
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