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Article

Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers.

Journal of clinical pharmacology - 1 Jul 2011

Nishino Masafumi, Sugimoto Mitsushige, Kodaira Chise, Yamade Mihoko, Uotani Takahiro, Shirai Naohito, Ikuma Mutsuhiro, Tanaka Tatsuo, Sugimura Haruhiko, Hishida Akira, Furuta Takahisa

Abstract excerpt

The preventive effects of lansoprazole and famotidine on low-dose aspirin-induced gastric mucosal injury in relation to gastric acidity were compared in healthy Japanese volunteers. Fifteen Helicobacter pylori-negative volunteers with different CYP2C19 genotypes were randomly administered aspirin 100 mg, aspirin plus famotidine 20 mg twice daily, or aspirin plus lansoprazole 15 mg once daily for 7 days each in a...

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Source

Identifiers

PMID: 20663999
DOI: 10.1177/0091270010376194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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