Article
Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric pH in healthy volunteers.
Digestive diseases and sciences - 1 Jun 2010
Nishino Masafumi, Sugimoto Mitsushige, Kodaira Chise, Yamade Mihoko, Shirai Naohito, Ikuma Mutsuhiro, Tanaka Tatsuo, Sugimura Haruhiko, Hishida Akira, Furuta Takahisa
Abstract excerpt
BACKGROUND AND AIMS: Gastric acid plays an important role in the pathogenesis of gastric mucosal lesions. We investigated whether aspirin-induced gastric mucosal injury might have any association with the intragastric pH. MATERIALS AND METHODS: Fifteen healthy, Helicobacter pylori-negative volunteers randomly underwent the four different 7-day regimens: (1) aspirin 100 mg, (2) rabeprazole 10 mg, (3) aspirin 100...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
