Article
Antiplatelet drugs are a risk factor for esophageal mucosal injury.
Digestion - 1 Jan 2013
Sugimoto Mitsushige, Uotani Takahiro, Nishino Masafumi, Yamade Mihoko, Sahara Shu, Yamada Takanori, Osawa Satoshi, Sugimoto Ken, Umemura Kazuo, Watanabe Hiroshi, Miyajima Hiroaki, Furuta Takahisa
Abstract excerpt
BACKGROUND: In esophagus whether antiplatelet drugs, such as low-dose aspirin (LDA) and clopidogrel, induce mucosal injury by pH changes or by acid reflux is unclear. We designed to clarify which mechanism was responsible. METHODS: In study 1, 80 patients taking LDA and 80 age- and sex-matched subjects who underwent endoscopy for dyspeptic symptoms or for a health check-up were evaluated the endoscopic incidence...
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